Cissus quadrangularis, commonly known as Hadjod, is a plant deeply embedded in traditional herbal knowledge, especially in Ayurveda. Its name is inspired by its distinctive, angular stem structure, which resembles jointed segments. For generations, this botanical has been recognized in various cultural practices for its unique physical characteristics and its longstanding presence in traditional formulations. Different parts of the plant—such as the stem, leaves, and roots—have appeared in heritage-based preparations where it was valued for its naturally occurring compounds and its role in maintaining general harmony within traditional routines. Ancient texts and cultural records highlight its historic significance and the wide range of traditional applications associated with it.